Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904746 | 0.87 | HPGDS (0.51) | POLBMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL23905572 | 0.84 | KDM4E (0.47) | POLBMEN1KMT2ARXFP1HPGDS | |
| SCHEMBL23904867 | 0.84 | MEN1 (0.48) | POLBMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL23905617 | 0.82 | LMNA (0.50) | POLBMEN1KMT2ASMN1; SMN2HPGDS | |
| SCHEMBL23904745 | 0.82 | CA12 (0.50) | POLBKDM4ERAB9ALMNAF2 | |
| SCHEMBL23958791 | 0.82 | KMT2A (0.52) | POLBMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL30007169 | 0.81 | TSHR (0.45) | POLBSMN1; SMN2HPGDSHPGDKDM4E | |
| SCHEMBL23930220 | 0.75 | KDM4E (0.44) | POLBMEN1KMT2ARXFP1HPGDS | |
| SCHEMBL30211289 | 0.75 | KDM4E (0.44) | POLBMEN1KMT2ARXFP1HPGDS | |
| SCHEMBL23930093 | 0.73 | CA12 (0.39) | POLBSMN1; SMN2KDM4ERAB9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |