Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RHOC | P08134 | 1/20 | 0.30 |
| ▸ | RHOA | P61586 | 1/20 | 0.30 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905687 | 0.94 | CFTR (0.33) | GABRA5MAPT | |
| SCHEMBL23905664 | 0.93 | MAPT (0.33) | MAPTTP53 | |
| SCHEMBL23905686 | 0.91 | PPARD (0.30) | — | |
| SCHEMBL23905573 | 0.91 | PPARD (0.30) | — | |
| SCHEMBL23905668 | 0.88 | CFTR (0.34) | GABRA5 | |
| SCHEMBL23905347 | 0.87 | CFTR (0.32) | GABRA5 | |
| SCHEMBL23905256 | 0.87 | CFTR (0.34) | GABRA5 | |
| SCHEMBL23905595 | 0.87 | CFTR (0.34) | GABRA5 | |
| SCHEMBL23905865 | 0.86 | GABRA5 (0.34) | GABRA5 | |
| SCHEMBL23905593 | 0.86 | CFTR (0.31) | GABRA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |