Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905616 | 0.88 | DPP4 (0.36) | GABRA5CNR2CNR1PTGS1PTGS2 | |
| SCHEMBL23905374 | 0.78 | CFTR (0.33) | GABRA5CYP2C9IDO1CYP3A4 | |
| SCHEMBL23905533 | 0.78 | CFTR (0.33) | GABRA5CYP2C9IDO1CYP3A4 | |
| SCHEMBL23905375 | 0.77 | CFTR (0.33) | CYP2C9IDO1 | |
| SCHEMBL26526016 | 0.77 | CFTR (0.32) | CYP2C9IDO1 | |
| SCHEMBL23195890 | 0.77 | CFTR (0.33) | CNR1CYP2C9IDO1 | |
| SCHEMBL24986093 | 0.77 | CFTR (0.41) | CYP2C9RORCIDO1MTORCYP3A4 | |
| SCHEMBL26526018 | 0.76 | CFTR (0.33) | CNR1CYP2C9IDO1 | |
| SCHEMBL23905407 | 0.74 | CFTR (0.33) | PTGS2CYP3A4 | |
| SCHEMBL23905581 | 0.74 | CFTR (0.33) | PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |