Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | STAMBP | O95630 | 1/20 | 0.32 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345454 | 0.94 | POLB (0.38) | POLBP2RX7KMT2AMEN1HPGD | |
| SCHEMBL24363611 | 0.94 | POLB (0.38) | POLBP2RX7KMT2AMEN1HPGD | |
| SCHEMBL23905666 | 0.90 | ROCK2 (0.33) | POLBROCK2ROCK1MAPTACSS2 | |
| SCHEMBL23905651 | 0.89 | ROCK2 (0.33) | P2RX7ROCK2ROCK1MAPT | |
| SCHEMBL23905464 | 0.89 | ROCK2 (0.33) | P2RX7ROCK2ROCK1MAPTMTTP | |
| SCHEMBL23905701 | 0.87 | AR (0.35) | POLB | |
| SCHEMBL23905426 | 0.84 | AR (0.34) | POLBP2RX7 | |
| SCHEMBL23905859 | 0.84 | POLB (0.36) | POLBP2RX7ROCK2ROCK1MAPT | |
| SCHEMBL23905711 | 0.82 | POLB (0.34) | POLBP2RX7ROCK2ROCK1MAPT | |
| SCHEMBL23904817 | 0.82 | LRRK2 (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |