Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.34 |
| ▸ | PDE4A | P27815 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904820 | 0.83 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL23195951 | 0.78 | CCR1 (0.39) | KMT2ALPAR1LPAR5PDE4DPDE4A | |
| SCHEMBL23904835 | 0.76 | SCD (0.39) | KMT2APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23905788 | 0.72 | KMT2A (0.45) | KMT2ALPAR1LPAR5PDE4DPDE4A | |
| SCHEMBL25116096 | 0.72 | KMO (0.40) | KMT2APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23904799 | 0.72 | KMT2A (0.41) | KMT2APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23195900 | 0.72 | KMO (0.44) | KMT2APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23904780 | 0.72 | KDM4E (0.43) | KMT2A | |
| SCHEMBL23904830 | 0.72 | KMT2A (0.44) | KMT2APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23905741 | 0.72 | HSD17B2 (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |