Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | PTGFR | P43088 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904880 | 0.91 | PTGFR (0.33) | GABRA5PTGFRLMNATP53P2RX7 | |
| SCHEMBL23905675 | 0.90 | PTGFR (0.32) | PTGFRLMNATP53 | |
| SCHEMBL23905985 | 0.88 | PTGFR (0.31) | PTGFRLMNATP53 | |
| SCHEMBL23905547 | 0.88 | LMNA (0.32) | PTGFRLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL23905672 | 0.86 | — | — | |
| SCHEMBL23905889 | 0.85 | PTGFR (0.33) | PTGFRLMNATP53 | |
| SCHEMBL23905665 | 0.85 | MAPT (0.33) | PTGFRTP53 | |
| SCHEMBL23905865 | 0.84 | GABRA5 (0.34) | GABRA5ABCB1ABCC1 | |
| SCHEMBL23905315 | 0.84 | GABRA5 (0.34) | GABRA5ABCB1ABCC1 | |
| SCHEMBL23905641 | 0.83 | LMNA (0.33) | GABRA5LMNATP53P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |