Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905974 | 0.84 | MAOB (0.57) | MRGPRX4GRM5MAOBLTB4RLTB4R2 | |
| SCHEMBL23905175 | 0.77 | MRGPRX4 (0.47) | MRGPRX4GRM5MAOBLTB4RLTB4R2 | |
| SCHEMBL12316573 | 0.77 | LTB4R (0.47) | MRGPRX4GRM5MAOBLTB4RLTB4R2 | |
| SCHEMBL12316589 | 0.76 | MRGPRX4 (0.57) | MRGPRX4GRM5MAOBLTB4RLTB4R2 | |
| SCHEMBL23906010 | 0.76 | MRGPRX4 (0.49) | MRGPRX4GRM5MAOBLTB4RLTB4R2 | |
| SCHEMBL9465539 | 0.75 | LMNA (0.54) | MRGPRX4GRM5MAOBLTB4RLTB4R2 | |
| SCHEMBL20554848 | 0.75 | MAOB (0.45) | GRM5MAOBLTB4RLTB4R2LMNA | |
| SCHEMBL30132607 | 0.75 | MAOB (0.45) | GRM5MAOBLTB4RLTB4R2LMNA | |
| SCHEMBL23905906 | 0.74 | MAOB (0.57) | MRGPRX4GRM5MAOB | |
| SCHEMBL23905919 | 0.72 | MAOB (0.59) | MRGPRX4GRM5MAOBLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |