Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23906313 | 0.80 | MAOB (0.46) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL23905175 | 0.80 | MRGPRX4 (0.47) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL23905999 | 0.78 | GRM5 (0.42) | GRM5PIK3CDMAOBALDH1A1NPC1 | |
| SCHEMBL23905984 | 0.78 | LTB4R (0.47) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL23905943 | 0.77 | GRM5 (0.41) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL23905925 | 0.76 | LTB4R (0.59) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL30251291 | 0.75 | MAPT (0.51) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL23882923 | 0.75 | MAPT (0.51) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL20554658 | 0.75 | MAOB (0.55) | GRM5MAOBALDH1A1NPC1HPGD | |
| SCHEMBL30132594 | 0.75 | MAOB (0.55) | GRM5MAOBALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |