Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.41 |
| ▸ | MAOB | P27338 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882644 | 0.85 | MAOB (0.47) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23905175 | 0.85 | MRGPRX4 (0.47) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23906313 | 0.85 | MAOB (0.46) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL32675527 | 0.84 | MAOB (0.42) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23882634 | 0.84 | MAOB (0.42) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23906005 | 0.84 | RXRA (0.46) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23905999 | 0.83 | GRM5 (0.42) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23905984 | 0.83 | LTB4R (0.47) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23905925 | 0.81 | LTB4R (0.59) | GRM5MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL23905955 | 0.78 | GRM5 (0.60) | GRM5MAOBNPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |