Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748985 | 0.90 | CHRNB2 (0.46) | PDPK1SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL24317225 | 0.78 | CHRNB2 (0.36) | PDPK1SIGMAR1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL10297727 | 0.76 | SIGMAR1 (0.42) | SIGMAR1CHRNB2CHRNA4CHRNA7DRD2 | |
| SCHEMBL61509 | 0.73 | PDPK1 (1.00) | PDPK1ACHEIDO1MAOAMAOB | |
| SCHEMBL2465738 | 0.73 | PDPK1 (1.00) | PDPK1ACHEIDO1MAOAMAOB | |
| SCHEMBL61508 | 0.73 | PDPK1 (1.00) | PDPK1ACHEIDO1MAOAMAOB | |
| SCHEMBL29395031 | 0.73 | PDPK1 (1.00) | PDPK1ACHEIDO1MAOAMAOB | |
| SCHEMBL14612385 | 0.73 | PDPK1 (1.00) | PDPK1ACHEIDO1MAOAMAOB | |
| SCHEMBL13271000 | 0.73 | SIGMAR1 (0.39) | SIGMAR1CHRNB2CHRNA4CHRNA7DRD2 | |
| SCHEMBL14490412 | 0.73 | SIGMAR1 (0.39) | SIGMAR1CHRNB2CHRNA4CHRNA7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |