Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319284 | 0.80 | POLB (0.46) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL17142292 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL7124026 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL2112642 | 0.78 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL29869611 | 0.78 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL27736885 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL27777942 | 0.73 | HPGD (0.39) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL27777943 | 0.73 | HPGD (0.39) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL29427040 | 0.72 | L3MBTL1 (0.47) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL19412400 | 0.72 | L3MBTL1 (0.47) | ALDH1A1HPGDMAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195782-A1 | METHODS OF USING MYT1 INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2021-10-07 | — | — | WO | disclosed |