Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | FUT4 | P22083 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286798 | 0.87 | KDM4E (0.43) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL16056737 | 0.86 | PDK2 (0.46) | ALDH1A1MAPTPDK2HDAC4GYS1 | |
| SCHEMBL30253983 | 0.81 | LMNA (0.45) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL17119839 | 0.81 | LMNA (0.45) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL29178465 | 0.80 | ESR1 (0.53) | HDAC4ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL11637605 | 0.80 | LMNA (0.59) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL10795881 | 0.78 | HDAC4 (0.54) | ALDH1A1HPGDSMN1; SMN2PDK2HDAC4 | |
| SCHEMBL23914114 | 0.78 | KDM4E (0.47) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL18652173 | 0.76 | SERPINE1 (0.45) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL12218597 | 0.76 | PDK2 (0.46) | TDP1ALDH1A1MAPTTP53BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198883-A1 | SYNTHESIS OF OLIGONUCLEOTIDES AND RELATED COMPOUNDS | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |