SCHEMBL23914114

SCHEMBL23914114

CN(CC(=O)O)C(=O)c1cc(O)c(O)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
LMNA P02545 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
FUT7 Q11130 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
TP53 P04637 1/20 0.47
CA3 P07451 1/20 0.47
SELL P14151 1/20 0.47
HPGD P15428 1/20 0.47
SELP P16109 1/20 0.47
FUT4 P22083 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
DPP4 P27487 1/20 0.47
MAPK1 P28482 1/20 0.47
CA5A P35218 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17119839 0.81 LMNA (0.45) KDM4ELMNATDP1ALDH1A1MAPT
SCHEMBL13286798 0.79 KDM4E (0.43) KDM4ELMNATDP1ALDH1A1MAPT
SCHEMBL11107022 0.78 HDAC1 (0.45) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL29317376 0.78 DRD3 (0.38) TDP1L3MBTL1CASP6PDK1PDK2
SCHEMBL23906976 0.78 KDM4E (0.42) KDM4ELMNATDP1ALDH1A1MAPT
SCHEMBL23914113 0.77 SERPINE1 (0.43) KDM4ELMNATDP1ALDH1A1MAPT
SCHEMBL18652173 0.76 SERPINE1 (0.45) KDM4ELMNATDP1ALDH1A1MAPT
SCHEMBL2119014 0.76 KDM4E (0.52) KDM4ELMNATDP1ALDH1A1MAPT
SCHEMBL2282162 0.75 KMT2A (0.53) ALDH1A1HPGDDPP4MEN1KMT2A
Hydrochloric Acid SCHEMBL1372985 0.73 KMT2A (0.51) ALDH1A1MAPTHPGDDPP4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20210317159-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT KDM4E 3094/4885LMNA 274/4885TDP1 538/4885
US-20210317159-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT KDM4E 3094/4885LMNA 274/4885TDP1 538/4885
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT KDM4E 3094/4885LMNA 274/4885TDP1 538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.