Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.78 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.78 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.75 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907461 | 0.99 | TAS1R3 (0.77) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL23907421 | 0.98 | TAS1R3 (0.75) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL23907435 | 0.97 | TAS1R3 (0.72) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL17824354 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL30969947 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL20282632 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL20282633 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL30969949 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL20277517 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1ADORA3GPR17 | |
| SCHEMBL21839754 | 0.86 | TAS1R3 (0.81) | TAS1R3TAS1R1ADORA1ADORA3GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | PELOTON THERAPEUTICS INC. (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210317150-A1 | CD73 INHIBITORS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | ENTPD5, ENTPD1, ENTPD3 | TAS1R3 2590/4885TAS1R1 2798/4885ADORA1 16/4885 |
| US-20210317150-A1 | CD73 INHIBITORS AND USES THEREOF | ENTPD5, ENTPD1, NT5E | TAS1R3 3522/4885TAS1R1 3109/4885ADORA1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.