Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.57 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391367 | 0.97 | SMN1; SMN2 (0.73) | NPC1RAB9ASMN1; SMN2TP53PAX8 | |
| SCHEMBL18587976 | 0.85 | YTHDC1 (0.59) | NPC1RAB9ASMN1; SMN2TP53PAX8 | |
| SCHEMBL29664960 | 0.85 | YTHDC1 (0.59) | NPC1RAB9ASMN1; SMN2TP53PAX8 | |
| SCHEMBL30410701 | 0.85 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2TP53PAX8 | |
| SCHEMBL29659620 | 0.84 | YTHDC1 (0.51) | NPC1RAB9ASMN1; SMN2ADORA3CCNB2 | |
| SCHEMBL20547532 | 0.84 | YTHDC1 (0.51) | NPC1RAB9ASMN1; SMN2ADORA3CCNB2 | |
| SCHEMBL20547474 | 0.84 | FLT3 (0.49) | NPC1RAB9ASMN1; SMN2ADORA3CCNB2 | |
| SCHEMBL18587971 | 0.83 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2TP53PAX8 | |
| SCHEMBL18587805 | 0.83 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2TP53PAX8 | |
| SCHEMBL20547431 | 0.83 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2TP53PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | disclosed |
| EP-3341371-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | Univerzita Palackého V Olomouci (CZ) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036434-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2017-03-09 | — | — | WO | disclosed |
| EP-2043630-B1 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES FOR COSMETIC USE | INST OF EX BOTANY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2016-09-07 | — | — | EP | disclosed |
| US-20130072505-A1 | 6,9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE (CZ) | 2013-03-21 | — | — | US | disclosed |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE | 2011-09-15 | — | — | US | disclosed |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | SZUCOVA LUCIE | 2010-09-16 | — | — | US | disclosed |
| EP-2043630-A2 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE FOR TREATING SKIN | Institute of Experimental Botany, Academy of Sciences of the Czech Republic (CZ) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008770-A2 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE FOR TREATING SKIN | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-17 | — | — | WO | disclosed |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | UNG, P2RY6, MPG | NPC1 3196/4885RAB9A 1395/4885SMN1; SMN2 3167/4885 |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | NPC1 3196/4885RAB9A 1395/4885SMN1; SMN2 3167/4885 |
| US-20130072505-A1 | 6,9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | NPC1 3196/4885RAB9A 1395/4885SMN1; SMN2 3167/4885 |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | UNG, P2RY6, MPG | NPC1 3196/4885RAB9A 1395/4885SMN1; SMN2 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.