Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390773 | 0.97 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL30409552 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL29659519 | 0.85 | YTHDC1 (0.64) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL20547190 | 0.85 | YTHDC1 (0.64) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL29659534 | 0.85 | YTHDC1 (0.55) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL20547188 | 0.85 | YTHDC1 (0.55) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL30410457 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL29366631 | 0.85 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL218275 | 0.85 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD | |
| SCHEMBL20547610 | 0.84 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9ACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250241848-A1 | NANOPARTICLE COMPOSITIONS, FORMULATIONS THEREOF, AND USES THEREFOR | ANTERIOS, INC. (US) | 2025-07-31 | — | — | US | disclosed |
| EP-4532498-A1 | HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS | Univerzita Palackého v Olomouci (CZ) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023232171-A1 | HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2023-12-07 | — | — | WO | disclosed |
| US-20220387299-A1 | NANOPARTICLE COMPOSITIONS, FORMULATIONS THEREOF, AND USES THEREFOR | ANTERIOS, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | disclosed |
| US-10774084-B2 | Adenine derivatives and their use as UV-photoprotective agents | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-09-15 | — | — | US | disclosed |
| EP-3233861-B1 | 6,8-DISUBSTITUTED-9-(HETEROCYCLYL) PURINES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND THEIR USE IN COSMETIC AND MEDICINAL APPLICATIONS | USTAV EXPERIMENTALNI BOTANIKY AV CR V V I (CZ) | 2019-04-10 | — | — | EP | disclosed |
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2018-10-18 | — | — | US | disclosed |
| US-10093675-B2 | 6,8-disubstituted-9-(heterocyclyl)purines, compositions containing these derivatives and their use in cosmetic and medicinal applications | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2018-10-09 | — | — | US | disclosed |
| EP-3341371-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | Univerzita Palackého V Olomouci (CZ) | 2018-07-04 | — | — | EP | disclosed |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE | 2011-09-15 | — | — | US | disclosed |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE | 2011-09-15 | — | — | US | disclosed |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | SZUCOVA LUCIE | 2010-09-16 | — | — | US | disclosed |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | SZUCOVA LUCIE | 2010-09-16 | — | — | US | disclosed |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | SZUCOVA LUCIE | 2010-09-16 | — | — | US | disclosed |
| EP-2043630-A2 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE FOR TREATING SKIN | Institute of Experimental Botany, Academy of Sciences of the Czech Republic (CZ) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008770-A2 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE FOR TREATING SKIN | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-17 | — | — | WO | disclosed |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-10 | — | — | US | disclosed |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-10 | — | — | US | disclosed |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250241848-A1 | NANOPARTICLE COMPOSITIONS, FORMULATIONS THEREOF, AND USES THEREFOR | TSG101, NPC1L1, NPC1 | SMN1; SMN2 299/4885NPC1 3/4885RAB9A 417/4885 |
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | XPA, ERCC4, UNG | SMN1; SMN2 3882/4885NPC1 3189/4885RAB9A 252/4885 |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | UNG, P2RY6, MPG | SMN1; SMN2 3167/4885NPC1 3196/4885RAB9A 1395/4885 |
| US-20220387299-A1 | NANOPARTICLE COMPOSITIONS, FORMULATIONS THEREOF, AND USES THEREFOR | TSG101, NPC1L1, NPC1 | SMN1; SMN2 299/4885NPC1 3/4885RAB9A 417/4885 |
| US-10093675-B2 | 6,8-disubstituted-9-(heterocyclyl)purines, compositions containing these derivatives and their use in cosmetic and medicinal applications | PNP, UNG, NUDT1 | SMN1; SMN2 3293/4885NPC1 3580/4885RAB9A 1999/4885 |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | SMN1; SMN2 3167/4885NPC1 3196/4885RAB9A 1395/4885 |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | UNG, P2RY6, MPG | SMN1; SMN2 3167/4885NPC1 3196/4885RAB9A 1395/4885 |
| US-10774084-B2 | Adenine derivatives and their use as UV-photoprotective agents | XPA, ERCC4, UNG | SMN1; SMN2 3861/4885NPC1 3283/4885RAB9A 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.