Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908280 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTTDP1KDM4E | |
| SCHEMBL5518041 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTHCAR3KMT2A | |
| SCHEMBL5518040 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTHCAR3KMT2A | |
| SCHEMBL5697787 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTTDP1KDM4E | |
| SCHEMBL3491006 | 0.74 | KMT2A (0.59) | ALDH1A1MAPTHTTTDP1KDM4E | |
| SCHEMBL17967396 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTHCAR3KMT2A | |
| SCHEMBL7808225 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTTDP1KDM4E | |
| SCHEMBL17070949 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTHTTTDP1KDM4E | |
| SCHEMBL7223000 | 0.70 | L3MBTL1 (0.46) | ALDH1A1MAPTTDP1KDM4EKMT2A | |
| SCHEMBL2675557 | 0.70 | TDP1 (0.56) | ALDH1A1MAPTHTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643438-B2 | Antimicrobial peptides and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2023-05-09 | — | — | US | disclosed |
| US-20210317167-A1 | ANTIMICROBIAL PEPTIDES AND METHODS OF USE | UNIV OKLAHOMA (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643438-B2 | Antimicrobial peptides and methods of use | VIP, NISCH, PTMA | ALDH1A1 4238/4885MAPT 2187/4885HTT 714/4885 |
| US-20210317167-A1 | ANTIMICROBIAL PEPTIDES AND METHODS OF USE | VIP, NISCH, PTMA | ALDH1A1 4238/4885MAPT 2187/4885HTT 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.