Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248471 | 0.86 | GAA (0.46) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL6834041 | 0.82 | HTT (0.42) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL6201094 | 0.81 | MAPT (0.52) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL9396474 | 0.80 | MAPT (0.42) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL215272 | 0.77 | HDAC3 (0.50) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL867417 | 0.77 | PRSS1 (0.47) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL10498975 | 0.77 | MAPT (0.46) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL6968841 | 0.77 | GAA (0.43) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL2228032 | 0.77 | HTT (0.67) | GAAHTTALDH1A1MAPTKDM4E | |
| SCHEMBL6966695 | 0.77 | MAPT (0.42) | GAAHTTALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317157-A1 | Substituted Alloxazine Nucleosides and Nucleotides, and Methods of Making Same | UNIV COLORADO REGENTS (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317157-A1 | Substituted Alloxazine Nucleosides and Nucleotides, and Methods of Making Same | UNIV COLORADO REGENTS (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317157-A1 | Substituted Alloxazine Nucleosides and Nucleotides, and Methods of Making Same | NT5C2, PNP, SLC35B2 | GAA 1262/4885HTT 2007/4885ALDH1A1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.