Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215272 | 0.95 | HDAC3 (0.50) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL8720375 | 0.93 | HDAC3 (0.53) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL6247309 | 0.93 | HDAC3 (0.53) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL6201094 | 0.90 | MAPT (0.52) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL9320885 | 0.89 | KAT2B (0.54) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL659537 | 0.87 | TLR8 (0.54) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL29636805 | 0.87 | TLR8 (0.54) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL4193150 | 0.87 | ALDH1A1 (0.51) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL30128568 | 0.87 | ALDH1A1 (0.51) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL27939188 | 0.87 | HDAC3 (0.42) | PRSS1MAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250180952-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2025-06-05 | — | — | US | disclosed |
| EP-4493638-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023174773-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2023-09-21 | — | — | WO | disclosed |
| US-11634544-B2 | Photoaligning materials | Rolic Technologies AG (CH) | 2023-04-25 | — | — | US | disclosed |
| US-20210340330-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2021-11-04 | — | — | US | disclosed |
| US-20200223984-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2020-07-16 | — | — | US | disclosed |
| US-10696795-B2 | Photoaligning materials | Rolic Technologies AG (CH) | 2020-06-30 | — | — | US | disclosed |
| EP-3374467-B1 | COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS | ROLIC TECH AG (CH) | 2020-04-15 | — | — | EP | disclosed |
| US-10558089-B2 | Photoalignment composition | ROLIC AG (CH) | 2020-02-11 | — | — | US | disclosed |
| EP-2222815-B1 | PHOTOALIGNMENT COMPOSITION | ROLIC TECH AG (CH) | 2019-05-29 | — | — | EP | disclosed |
| US-20080227961-A1 | BRIDGED AROMATIC SUBSTITUTED AMINE LIGANDS WITH DONOR ATOMS | PONIARD PHARMACEUTICALS, INC.. | 2008-09-18 | — | — | US | disclosed |
| US-7268220-B2 | Bridged aromatic substituted amine ligands with donor atoms | PONIARD PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268220-B2 | Bridged aromatic substituted amine ligands with donor atoms | PONIARD PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-6569880-B2 | Guanidine derivatives | NEUROSEARCH A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| US-20020137784-A1 | Potassium channel blocking agents | NEUROSEARCH A/S | 2002-09-26 | — | — | US | disclosed |
| US-6380180-B1 | BENZIMIDAZOLE COMPOUNDS FOR TREATMENT OF ASTHMA, VASOSPASM, MEMORY LOSS, MIGRAINE AND OTHERS DISEASES ASSOCIATED WITH POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 2002-04-30 | — | — | US | disclosed |
| US-20020049246-A1 | Potassium channel blocking agents | NEUROSEARCH A/S | 2002-04-25 | — | — | US | disclosed |
| EP-1091942-A1 | POTASSIUM CHANNEL BLOCKING AGENTS | NEUROSEARCH A/S (DK) | 2001-04-18 | — | — | EP | disclosed |
| US-6194447-B1 | ASTHMA, ANTICONVULSANTS, COGNITION ACTIVATORS, BRAIN DISORDERS, PSYCHOLOGICAL DISORDERS, CARDIOVASCULAR DISORDERS,GASTROINTESTINAL DISORDERS | NEUROSEARCH A/S (DK) | 2001-02-27 | — | — | US | disclosed |
| WO-2000001676-A1 | POTASSIUM CHANNEL BLOCKING AGENTS | NEUROSEARCH A/S (DK) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227961-A1 | BRIDGED AROMATIC SUBSTITUTED AMINE LIGANDS WITH DONOR ATOMS | AOC1, DDC, SLC30A5 | PRSS1 4683/4885MAPT 1594/4885ALDH1A1 1255/4885 |
| US-20020137784-A1 | Potassium channel blocking agents | KCNH2, KCNH3, KCND2 | PRSS1 449/4885MAPT 918/4885ALDH1A1 3057/4885 |
| US-20020049246-A1 | Potassium channel blocking agents | KCNH2, KCNH3, KCND2 | PRSS1 449/4885MAPT 918/4885ALDH1A1 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.