Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorpyrifos-Methyl SCHEMBL27546 | 0.76 | TDP1 (1.00) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos-Methyl SCHEMBL21647865 | 0.76 | TDP1 (1.00) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL30538657 | 0.76 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL6736860 | 0.76 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL117867 | 0.76 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL31254099 | 0.72 | TDP1 (0.58) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11749341 | 0.72 | TDP1 (0.58) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11416872 | 0.71 | TDP1 (0.67) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11312487 | 0.70 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11317244 | 0.70 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |