Fospirate

Fospirate

SCHEMBL6736860

COP(=O)(OC)Oc1nc(Cl)c(Cl)cc1Cl.COP(=O)(OC)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
ALDH1A1 P00352 2/20 0.51
CYP3A4 P08684 2/20 0.51
TSHR P16473 2/20 0.51
MAPT P10636 1/20 0.51
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
MAPK1 P28482 1/20 0.51
ATM Q13315 1/20 0.51
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fospirate SCHEMBL117867 1.00 TDP1 (0.65) TDP1MEN1KMT2AALDH1A1CYP3A4
Fospirate SCHEMBL30538657 1.00 TDP1 (0.65) TDP1MEN1KMT2AALDH1A1CYP3A4
Chlorphrifos Oxon SCHEMBL30674408 0.81 TDP1 (0.68) TDP1MEN1KMT2AALDH1A1CYP3A4
Chlorphrifos Oxon SCHEMBL1168184 0.81 TDP1 (0.68) TDP1MEN1KMT2AALDH1A1CYP3A4
Chlorpyrifos-Methyl SCHEMBL27546 0.79 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1CYP3A4
Chlorpyrifos-Methyl SCHEMBL21647865 0.79 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL678129 0.78 TDP1 (0.47) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL16506502 0.78 TDP1 (0.54) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL23909408 0.76 TDP1 (0.61) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL990015 0.75 TDP1 (0.51) TDP1MEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680065-B2 FOR TREATMENT OF WOODY PLANTS; EMPLOYED IN HOLLOW PREFORMED IN THE WOODY PLANT BAYER AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6528079-B2 For treatment of woody plants; employed in a hollow preformed in the woody plant BAYER AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-23 US disclosed
US-20010039248-A1 Shaped bodies which release agrochemical active substances PODSZUN WOLFGANG (DE) 2001-11-08 US disclosed
EP-0564945-B1 A method of controlling harmful insects BAYER AGROCHEM KK (JP) 2001-01-24 EP disclosed
CN-1054261-C Plant treatment agents BAYER AGROCHEM KK (JP) 2000-07-12 CN disclosed
US-6063393-A RODS OR PINS TO BE PRESSED INTO PLANTS NIHON BAYER AGROCHEM K.K. (JP) 2000-05-16 US disclosed
CN-1078850-A The method of control harmful insect BAYER AGROCHEM KK (JP) 1993-12-01 CN disclosed
EP-0564945-A1 A method of controlling harmful insects NIHON BAYER AGROCHEM K.K. (JP) 1993-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES AGL, CHMP4B, GUSB TDP1 2179/4885MEN1 2533/4885KMT2A 2911/4885
US-20010039248-A1 Shaped bodies which release agrochemical active substances AGL, CHMP4B, GUSB TDP1 2138/4885MEN1 2389/4885KMT2A 2896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.