Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.40 |
| ▸ | FEN1 | P39748 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909948 | 0.86 | KDM4E (0.39) | CYP11B1CYP11B2KDM4EAAK1MAPT | |
| SCHEMBL23909982 | 0.85 | AR (0.39) | ALOX5APFEN1KDM4EAAK1MAPT | |
| SCHEMBL21072099 | 0.81 | KDM4E (0.42) | CYP11B1CYP11B2KDM4EMAPTTDP1 | |
| SCHEMBL20329654 | 0.79 | PIK3CD (0.43) | CYP11B1CYP11B2KDM4EMAPTALDH1A1 | |
| SCHEMBL21071523 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2KDM4EMAPTTDP1 | |
| SCHEMBL23916412 | 0.74 | BRAF (0.34) | ALOX5APFEN1AAK1MAPTTDP1 | |
| SCHEMBL23910057 | 0.73 | KDM4E (0.44) | CYP11B1CYP11B2ALOX5APFEN1KDM4E | |
| SCHEMBL13514630 | 0.72 | KDM4E (0.40) | CYP11B1CYP11B2KDM4EAAK1MAPT | |
| SCHEMBL23910091 | 0.72 | KDM4E (0.40) | KDM4EMAPTALDH1A1USP2RET | |
| SCHEMBL23915999 | 0.71 | ALOX5AP (0.39) | CYP11B1CYP11B2ALOX5APFEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | CYP11B1 143/4885CYP11B2 79/4885ALOX5AP 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.