Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073058 | 0.82 | TSHR (0.50) | EPHX2MEN1GAAKMT2ACA12 | |
| SCHEMBL10045818 | 0.82 | EPHX2 (0.38) | TDP1EPHX2MLYCDCYP2D6DGAT1 | |
| SCHEMBL17222818 | 0.77 | EPHX2 (0.40) | TDP1EPHX2MLYCDCYP2D6DGAT1 | |
| SCHEMBL3485766 | 0.77 | EPHX2 (0.40) | TDP1EPHX2MLYCDCYP2D6DGAT1 | |
| SCHEMBL17243980 | 0.76 | HRH3 (0.41) | TDP1EPHX2CYP2D6DGAT1HDAC3 | |
| SCHEMBL410766 | 0.75 | EPHX2 (0.39) | TDP1EPHX2MLYCDCYP2D6DGAT1 | |
| SCHEMBL16887385 | 0.75 | EPHX2 (0.39) | TDP1EPHX2MLYCDCYP2D6DGAT1 | |
| SCHEMBL6191373 | 0.74 | TDP1 (0.42) | TDP1EPHX2MLYCDCYP2D6DGAT1 | |
| Hydrochloric Acid SCHEMBL8024182 | 0.74 | — | — | |
| SCHEMBL10209390 | 0.74 | EPHX2 (0.38) | TDP1EPHX2MLYCDCYP2D6DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317071-A1 | PH-RESPONSIVE LIPIDS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2021-10-14 | — | — | US | disclosed |
| US-20210317071-A1 | PH-RESPONSIVE LIPIDS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317071-A1 | PH-RESPONSIVE LIPIDS | FASN, ELOVL1, FFAR1 | TDP1 4412/4885EPHX2 154/4885MLYCD 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.