Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23910549 | 0.82 | TDP1 (0.37) | TSHRCA12CA14KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8024182 | 0.79 | — | — | |
| SCHEMBL11429347 | 0.79 | TSHR (0.46) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL18857802 | 0.77 | TET2 (0.46) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL420456 | 0.77 | TSHR (0.55) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL8024030 | 0.75 | LMNA (0.38) | TSHRLMNAKDM4E | |
| SCHEMBL21787660 | 0.73 | — | — | |
| SCHEMBL14565928 | 0.72 | TSHR (0.54) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL1188784 | 0.72 | TSHR (0.48) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL19961106 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009114854-A1 | BIODEGRADABLE CROSS-LINKED BRANCHED POLY (ALKYLENE IMINES) | EGEN, INC. (US) | 2009-09-17 | — | — | WO | disclosed |