Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 15/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23910869 | 1.00 | USP7 (0.77) | USP7ALDH1A1ACVR1JAK3IRAK4 | |
| SCHEMBL23910650 | 0.95 | USP7 (0.72) | USP7ACVR1JAK3 | |
| SCHEMBL23910652 | 0.95 | USP7 (0.72) | USP7ACVR1JAK3 | |
| SCHEMBL23910805 | 0.95 | USP7 (0.72) | USP7ACVR1JAK3 | |
| SCHEMBL23910946 | 0.92 | USP7 (0.74) | USP7ACVR1 | |
| SCHEMBL23910944 | 0.92 | USP7 (0.74) | USP7ACVR1 | |
| SCHEMBL23911107 | 0.90 | USP7 (0.70) | USP7JAK3 | |
| SCHEMBL23911105 | 0.90 | USP7 (0.70) | USP7JAK3 | |
| SCHEMBL23910683 | 0.89 | USP7 (0.76) | USP7ALDH1A1ACVR1IRAK4 | |
| SCHEMBL23921776 | 0.89 | USP7 (0.84) | USP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | USP7 1/4885ALDH1A1 3068/4885ACVR1 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.