SCHEMBL23910946

SCHEMBL23910946

CN(C)C1CN(C(=O)C2Cc3cc(Cl)cc(-c4ccnc5ccsc45)c3O2)C1

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 15/20 0.74
EIF4EBP1 Q13541 2/20 0.33
SCN3A Q9NY46 1/20 0.33
ACVR1 Q04771 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23910944 1.00 USP7 (0.74) USP7EIF4EBP1SCN3AACVR1
SCHEMBL23910650 0.93 USP7 (0.72) USP7EIF4EBP1ACVR1
SCHEMBL23910805 0.93 USP7 (0.72) USP7EIF4EBP1ACVR1
SCHEMBL23910652 0.93 USP7 (0.72) USP7EIF4EBP1ACVR1
SCHEMBL23911105 0.92 USP7 (0.70) USP7
SCHEMBL23911107 0.92 USP7 (0.70) USP7
SCHEMBL23910869 0.92 USP7 (0.77) USP7ACVR1
SCHEMBL23910866 0.92 USP7 (0.77) USP7ACVR1
SCHEMBL23910729 0.87 USP7 (0.74) USP7
SCHEMBL23910725 0.87 USP7 (0.74) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 USP7 1/4885EIF4EBP1 2219/4885SCN3A 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.