Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23911681 | 1.00 | MEN1 (0.72) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL3631391 | 0.91 | MEN1 (0.89) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL18732402 | 0.91 | MEN1 (0.89) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL23921025 | 0.87 | KMT2A (0.56) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL5950610 | 0.87 | MAPT (0.95) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL18270323 | 0.84 | MEN1 (0.76) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL58442 | 0.84 | MEN1 (1.00) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL4943174 | 0.83 | MAPT (1.00) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL4348467 | 0.83 | RAB9A (0.59) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL6550571 | 0.83 | RAB9A (0.59) | MEN1KMT2ARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142500-B2 | Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same | UNIVERSITY OF OREGON (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142500-B2 | Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same | MYC, KRAS, NRAS | MEN1 145/4885KMT2A 2503/4885RAB9A 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.