Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL1831655 | 0.81 | WDR5 (0.66) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| SCHEMBL344095 | 0.81 | HSD17B10 (0.59) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| SCHEMBL1661024 | 0.79 | HSD17B10 (0.63) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| SCHEMBL10783918 | 0.79 | MEN1 (0.57) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| Benzene SCHEMBL10558251 | 0.78 | KDM4E (0.68) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| SCHEMBL70004 | 0.78 | KDM4E (0.68) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| SCHEMBL29599456 | 0.78 | KDM4E (0.68) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL122832 | 0.78 | MEN1 (1.00) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL29352186 | 0.78 | MEN1 (1.00) | KDM4EHSD17B10MEN1ALDH1A1HPGD | |
| SCHEMBL1809752 | 0.78 | HSD17B10 (0.61) | KDM4EHSD17B10MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142500-B2 | Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same | UNIVERSITY OF OREGON (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142500-B2 | Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same | MYC, KRAS, NRAS | KDM4E 2329/4885HSD17B10 4311/4885MEN1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.