Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15198874 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL15186966 | 0.78 | PRKCA (0.43) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL25518244 | 0.77 | MEN1 (0.42) | ALDH1A1LMNAMEN1CYP2C19RECQL | |
| SCHEMBL76782 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL5308587 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL23712105 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL17877418 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL23766663 | 0.76 | MAPT (0.32) | ALDH1A1LMNAMEN1CYP2C19RECQL | |
| SCHEMBL16687831 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL15198873 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11141495-B2 | MRI imaging of amyloid plaque using liposomes | TEXAS CHILDREN'S HOSPITAL (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141495-B2 | MRI imaging of amyloid plaque using liposomes | APP, PSEN2, APBA1 | ALDH1A1 4494/4885LMNA 1021/4885PRKCA 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.