Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL21253146 | 1.00 | DNM1 (0.44) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| Bromide SCHEMBL238106 | 1.00 | DNM1 (0.44) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| Bromide SCHEMBL28501646 | 1.00 | DNM1 (0.44) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| Bromide SCHEMBL4623968 | 1.00 | DNM1 (0.44) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| Bromide SCHEMBL60952 | 1.00 | DNM1 (0.44) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| Bromide SCHEMBL8471902 | 1.00 | DNM1 (0.44) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL12946732 | 0.97 | OPRM1 (0.46) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL37596 | 0.97 | OPRM1 (0.46) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL20747520 | 0.97 | OPRM1 (0.46) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL1024279 | 0.97 | OPRM1 (0.46) | DNM1OPRM1CHRNB2CHRNB4CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111698982-B | Hair treatment composition | 株式会社资生堂 | 2024-09-27 | — | — | CN | disclosed |
| CN-111698982-A | Hair treatment composition | 株式会社资生堂 | 2020-09-22 | — | — | CN | disclosed |
| WO-2019155968-A1 | HAIR TREATMENT COMPOSITION | 株式会社資生堂 | 2019-08-15 | — | — | WO | disclosed |
| US-8728229-B2 | Cement slurry composition | KAO CORPORATION (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20120000397-A1 | CEMENT SLURRY COMPOSITION | KAO CORPORATION (JP) | 2012-01-05 | — | — | US | disclosed |
| WO-2010143312-A1 | CEMENT SLURRY COMPOSITION | KAO CORPORATION (JP) | 2010-12-16 | — | — | WO | disclosed |