SCHEMBL23912141

SCHEMBL23912141

O=C1c2ccc(O)cc2C(O)C2C=CC(O)=CC12

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.39
ESR1 P03372 1/20 0.33
MAOA P21397 1/20 0.33
UGT1A1 P22309 1/20 0.33
MAOB P27338 1/20 0.33
ESR2 Q92731 1/20 0.33
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13316461 0.74 ESR2 (0.41) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL19456485 0.60 CYP2D6 (0.44)
SCHEMBL177986 0.55 MAOA (0.56) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL30828317 0.55 MAOA (0.56) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL18786964 0.55 MKNK2 (0.46) DYRK1AESR1MAOAUGT1A1MAOB
SCHEMBL23861534 0.54 CYP3A4 (0.36) ESR1MAOAMAOBESR2
SCHEMBL12189747 0.54 DYRK1A (0.42) DYRK1ACHRNB2CHRNA4
SCHEMBL1658268 0.53 DYRK1A (0.62) DYRK1AESR1MAOAUGT1A1MAOB
SCHEMBL7511155 0.53 ESR1 (0.58) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL29742702 0.53 DYRK1A (0.62) DYRK1AESR1MAOAUGT1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893272-A1 HIGH VOLTAGE CIRCUIT BOARD AND HIGH VOLTAGE DEVICE USING SAME Kuraray Co., Ltd. (JP) 2021-10-13 EP disclosed