SCHEMBL177986

SCHEMBL177986

O=C1NC(=O)c2cc(O)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.56
MAOB P27338 6/20 0.56
ESR1 P03372 1/20 0.56
UGT1A1 P22309 1/20 0.56
ESR2 Q92731 1/20 0.56
PPOX P50336 1/20 0.56
EGFR P00533 2/20 0.55
PRKD3 O94806 1/20 0.55
ABL1 P00519 1/20 0.55
PRKCG P05129 1/20 0.55
PRKCB P05771 1/20 0.55
SRC P12931 1/20 0.55
PRKCA P17252 1/20 0.55
PRKCH P24723 1/20 0.55
PRKCI P41743 1/20 0.55
ABL2 P42684 1/20 0.55
PRKCE Q02156 1/20 0.55
PRKCQ Q04759 1/20 0.55
PRKCZ Q05513 1/20 0.55
PRKCD Q05655 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30828317 1.00 MAOA (0.56) MAOAMAOBESR1UGT1A1ESR2
Benzaldehyde SCHEMBL29253163 0.82 ALDH1A1 (0.48) MAOAMAOBESR1EGFRPRKD3
SCHEMBL383829 0.76 MAOA (0.63) MAOAMAOBPPOXCA1CA2
SCHEMBL8319902 0.75 PPOX (0.60) MAOAMAOBPPOXGSK3BCYP3A4
SCHEMBL8962219 0.75 PPOX (0.60) MAOAMAOBPPOXGSK3BCYP3A4
Potassium SCHEMBL31268252 0.74 MAOA (0.61) MAOAMAOBPPOXCA1CA2
SCHEMBL11426691 0.74 MAOA (0.61) MAOAMAOBPPOXCA1CA2
SCHEMBL11435308 0.74 MAOA (0.61) MAOAMAOBPPOXCA1CA2
SCHEMBL11422269 0.74 MAOA (0.61) MAOAMAOBPPOXCA1CA2
Lithium SCHEMBL11426699 0.74 MAOA (0.61) MAOAMAOBPPOXCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290915-B Heat-resistant PET protective film and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-07-30 CN claimed
CN-118290915-A Heat-resistant PET protective film and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-07-05 CN claimed
CN-103896822-B A kind of 3, the synthetic method of the two phthalic imidine of 4 '-oxo YIZHENG HAIFAN CHEMICAL CO., LTD. (CN) 2016-02-10 CN claimed
CN-103896822-A Synthetic method of 3, 4'-oxo bisphthalimide YIZHENG HAIFAN CHEMICAL CO LTD 2014-07-02 CN claimed
EP-0195402-B1 BIS(HYDROXYPHTHALIMIDE) AND PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYESTERIMIDE BY THE USE THEREOF NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-10 EP claimed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US claimed
JP-10147064-A None JP disclosed
CN-121574723-A Application of pomalidomide and various derivatives thereof as electrochemiluminescence probes 厦门医学院 2026-02-27 CN disclosed
US-12251370-B2 Small molecule inhibitors of the BfrB:Bfd interaction BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2025-03-18 US disclosed
US-20240327412-A1 FACTOR XIIA INHIBITORS KALVISTA PHARMACEUTICALS LIMITED (GB) 2024-10-03 US disclosed
CN-118290915-B Heat-resistant PET protective film and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-07-30 CN disclosed
CN-118290915-A Heat-resistant PET protective film and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-07-05 CN disclosed
US-11912699-B2 Tau-protein targeting compounds and associated ARVINAS OPERATIONS, INC. (US) 2024-02-27 US disclosed
US-5821256-A Endothelin receptor antagonists MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-10-13 US disclosed
JP-H10147064-A REVERSIBLE HEAT-SENSITIVE COLORING COMPOSITION AND REVERSIBLE RECORDING MEDIUM USING THE SAME RICOH CO LTD 1998-06-02 JP disclosed
EP-0758650-A1 Endothelin receptor antagonists MERCK PATENT GmbH (DE) 1997-02-19 EP disclosed
US-5208364-A Antiinflammatory agents of amines with carboxy, oxy groups BRISTOL-MYERS SQUIBB CO. (US) 1993-05-04 US disclosed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912699-B2 Tau-protein targeting compounds and associated MAPT, VHL, CRBN MAOA 2592/4885MAOB 2985/4885ESR1 2710/4885
US-12251370-B2 Small molecule inhibitors of the BfrB:Bfd interaction BLVRB, TFPI, ETFB MAOA 787/4885MAOB 292/4885ESR1 2734/4885
US-20240327412-A1 FACTOR XIIA INHIBITORS F11, F13B, F12 MAOA 219/4885MAOB 102/4885ESR1 4135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.