SCHEMBL23912236

SCHEMBL23912236

c1ccc(-c2ccnc(-c3cccc4c3oc3ncccc34)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 12/20 0.55
PIM1 P11309 1/20 0.39
PIK3CA P42336 3/20 0.39
PIK3C2A O00443 1/20 0.39
PIK3C2B O00750 1/20 0.39
PIK3R1 P27986 1/20 0.39
PIK3C3 Q8NEB9 1/20 0.39
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TGFBR1 P36897 1/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP1B1 Q16678 1/20 0.35
CDK1 P06493 1/20 0.34
CCNB1 P14635 1/20 0.34
GSK3B P49841 1/20 0.34
CDK5 Q00535 1/20 0.34
CDK5R1 Q15078 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15672855 0.85 PRKDC (0.49) PRKDCPIM1TGFBR1
SCHEMBL15672991 0.83 PRKDC (0.48) PRKDCPIM1TGFBR1CYP1A2
SCHEMBL22722345 0.83 PRKDC (0.54) PRKDCPIM1PIK3CAALDH1A1TGFBR1
SCHEMBL15695118 0.82 ALDH1A1 (0.44) PRKDCPIM1PIK3CAPIK3C2APIK3C2B
SCHEMBL15672944 0.82 PRKDC (0.47) PRKDCPIM1TGFBR1TSHRMAPK1
SCHEMBL16441234 0.82 PRKDC (0.40) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1
SCHEMBL25716391 0.81 PIK3CA (0.37) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1
SCHEMBL26552631 0.81 PIK3CA (0.40) PRKDCPIM1PIK3CAPIK3C2APIK3C2B
SCHEMBL25636984 0.81 PRKDC (0.55) PRKDCPIM1PIK3CAKDM4EALDH1A1
SCHEMBL29906205 0.81 KDM4E (0.43) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-20230203076-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-06-29 US disclosed
US-11683981-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-20 US disclosed
US-11142538-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR PRKDC 4083/4885PIM1 4545/4885PIK3CA 4759/4885
US-11142538-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 PRKDC 4670/4885PIM1 3001/4885PIK3CA 4169/4885
US-11683981-B2 Organic electroluminescent materials and devices OXER1, CHRM1, OSBPL8 PRKDC 4513/4885PIM1 4478/4885PIK3CA 4753/4885
US-20230203076-A1 Organic electroluminescent materials and devices SSB, ADORA3, SNRPA1 PRKDC 4140/4885PIM1 2547/4885PIK3CA 2471/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR PRKDC 4083/4885PIM1 4545/4885PIK3CA 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.