Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912265 | 0.91 | PIK3CD (0.56) | HRH3KCNH2PIK3CD | |
| SCHEMBL23912243 | 0.87 | PIK3CD (0.50) | HRH3KCNH2PIK3CD | |
| SCHEMBL23912317 | 0.87 | PIK3CD (0.58) | HRH3KCNH2PIK3CD | |
| SCHEMBL23912303 | 0.84 | PIK3CD (0.57) | HRH3KCNH2PIK3CD | |
| SCHEMBL17458267 | 0.84 | PIK3CD (0.67) | HRH3KCNH2PIK3CD | |
| SCHEMBL19924358 | 0.84 | PIK3CD (0.67) | HRH3KCNH2PIK3CD | |
| SCHEMBL17458265 | 0.84 | PIK3CD (0.67) | HRH3KCNH2PIK3CD | |
| SCHEMBL19924360 | 0.84 | PIK3CD (0.67) | HRH3KCNH2PIK3CD | |
| SCHEMBL23912240 | 0.82 | PIK3CD (0.55) | HRH3KCNH2PIK3CD | |
| SCHEMBL17458018 | 0.81 | PIK3CD (0.64) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |