Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912317 | 0.91 | PIK3CD (0.58) | PIK3CDKCNH2HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL23912243 | 0.88 | PIK3CD (0.50) | PIK3CDKCNH2HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL23912265 | 0.86 | PIK3CD (0.56) | PIK3CDKCNH2HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL23912237 | 0.84 | HRH3 (0.59) | PIK3CDKCNH2HRH3 | |
| SCHEMBL23912240 | 0.75 | PIK3CD (0.55) | PIK3CDKCNH2HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL23912253 | 0.75 | SMN1; SMN2 (0.45) | PIK3CDKCNH2HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL20404284 | 0.74 | SMN1; SMN2 (0.48) | PIK3CDKCNH2HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL17458136 | 0.74 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL17458132 | 0.74 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL17458419 | 0.74 | PIK3CD (0.59) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |