Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912241 | 0.90 | HRH3 (0.60) | PIK3CDKCNH2HRH3MEN1KMT2A | |
| SCHEMBL23912309 | 0.90 | HRH3 (0.60) | PIK3CDKCNH2HRH3MEN1KMT2A | |
| SCHEMBL17458387 | 0.84 | PIK3CD (0.66) | PIK3CDKCNH2HRH3OXTRAVPR1A | |
| SCHEMBL17458389 | 0.84 | PIK3CD (0.66) | PIK3CDKCNH2HRH3OXTRAVPR1A | |
| SCHEMBL23912244 | 0.83 | PIK3CD (0.57) | PIK3CDHIF1AGAAKDM4EMEN1 | |
| SCHEMBL17458468 | 0.82 | PIK3CD (0.66) | PIK3CDPOLBKDM4E | |
| SCHEMBL23912265 | 0.82 | PIK3CD (0.56) | PIK3CDKCNH2HRH3GAAPOLB | |
| SCHEMBL17461938 | 0.77 | PIK3CD (0.62) | PIK3CDPOLBKDM4E | |
| SCHEMBL17457971 | 0.76 | PIK3CD (0.66) | PIK3CDKCNH2HRH3DRD1DRD5 | |
| SCHEMBL17457970 | 0.76 | PIK3CD (0.66) | PIK3CDKCNH2HRH3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |