Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458201 | 0.85 | PIK3CD (0.67) | PIK3CDALDH1A1FKBP1AHSP90AA1HSP90AB1 | |
| SCHEMBL17458199 | 0.85 | PIK3CD (0.67) | PIK3CDALDH1A1FKBP1AHSP90AA1HSP90AB1 | |
| SCHEMBL17458208 | 0.84 | PIK3CD (0.69) | PIK3CDALDH1A1SMN1; SMN2FKBP1AMAPT | |
| SCHEMBL23912306 | 0.83 | PIK3CD (0.56) | PIK3CDALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL23912248 | 0.80 | PIK3CD (0.56) | PIK3CDALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL17461936 | 0.79 | PIK3CD (0.64) | PIK3CDFKBP1AHSP90AA1HSP90AB1 | |
| SCHEMBL23912255 | 0.77 | PIK3CD (0.54) | PIK3CDALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL17458427 | 0.76 | PIK3CD (0.67) | PIK3CDALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL17458426 | 0.76 | PIK3CD (0.67) | PIK3CDALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL23912309 | 0.75 | HRH3 (0.60) | PIK3CDALDH1A1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |