Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084075 | 0.78 | TRIM24 (0.37) | HPGDLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL11858309 | 0.75 | KMT2A (0.54) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4521726 | 0.72 | SMN1; SMN2 (0.39) | HPGDLMNAL3MBTL1HTTALDH1A1 | |
| SCHEMBL25629535 | 0.72 | LMNA (0.51) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL609169 | 0.71 | CYP1A1 (0.51) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL20662464 | 0.69 | DDB1 (0.37) | HPGDL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4531563 | 0.68 | ALDH1A1 (0.40) | LMNAL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL8194084 | 0.68 | ALDH1A1 (0.40) | LMNAL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL21310359 | 0.65 | — | — | |
| SCHEMBL21310375 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |