SCHEMBL23912335

SCHEMBL23912335

CNc1cncc(Br)c1C=N

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 4/20 0.37
AOC3 Q16853 4/20 0.37
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17461534 0.72 PTGS1 (0.46)
SCHEMBL20519784 0.71 AOC1 (0.42) AOC1AOC3KDM4C
SCHEMBL22453622 0.70
SCHEMBL23912314 0.66 DRD1 (0.33)
SCHEMBL27254733 0.64
SCHEMBL16210646 0.64 NPSR1 (0.33)
SCHEMBL2415034 0.64 NPSR1 (0.33)
SCHEMBL12807740 0.63 AOC1 (0.34) AOC1AOC3KDM4C
SCHEMBL6871548 0.63
SCHEMBL9998811 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024042316-A1 PYRIDO-PYRAZOLES AS INHIBITORS OF DDR'S FOR THE TREATMENT OF FIBROTIC DISORDERS AND CANCER REDX PHARMA PLC. (GB) 2024-02-29 WO disclosed
EP-3892278-B1 CYCLOALKANE-1,3-DIAMINE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2024-02-28 EP disclosed
EP-3892278-A1 CYCLOALKANE-1,3-DIAMINE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2021-10-13 EP disclosed