Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912335 | 0.72 | AOC1 (0.37) | — | |
| SCHEMBL24283166 | 0.70 | MAPK10 (0.37) | PTGS1PTGS2ALDH1A1HTTRAB9A | |
| SCHEMBL17461539 | 0.69 | RAB9A (0.52) | PTGS1PTGS2ALDH1A1HTTRAB9A | |
| SCHEMBL567599 | 0.69 | GAA (0.44) | ALDH1A1HTTRAB9AKCNH2MAPT | |
| SCHEMBL13393519 | 0.68 | APP (0.33) | PTGS1PTGS2 | |
| SCHEMBL23904233 | 0.67 | MAPT (0.36) | KCNH2SCN5ASCN9ASOS1MAPT | |
| SCHEMBL20036833 | 0.66 | MAPT (0.41) | ALDH1A1HTTRAB9ASOS1MAPT | |
| SCHEMBL17461544 | 0.64 | MAPK10 (0.38) | PTGS1PTGS2ALDH1A1HTTRAB9A | |
| SCHEMBL17461535 | 0.64 | MAPT (0.41) | PTGS1PTGS2ALDH1A1HTTRAB9A | |
| SCHEMBL30494419 | 0.64 | CHRNB4 (0.48) | PTGS1PTGS2ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346868-B1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-01-27 | — | — | EP | disclosed |