Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | PPM1D | O15297 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794966 | 0.94 | LOXL2 (0.50) | CYP4A11LOXL2CYP4F2EPHX1MEN1 | |
| SCHEMBL6963348 | 0.87 | LOXL2 (0.54) | CYP4A11LOXL2CYP4F2PPM1DEPHX1 | |
| SCHEMBL31352725 | 0.84 | LOXL2 (0.58) | CYP4A11LOXL2CYP4F2EPHX1MEN1 | |
| SCHEMBL8703548 | 0.81 | CYP4A11 (0.51) | CYP4A11LOXL2CYP4F2EPHX1MEN1 | |
| SCHEMBL13687815 | 0.79 | LOXL2 (0.51) | CYP4A11LOXL2CYP4F2EPHX1MEN1 | |
| SCHEMBL2250651 | 0.77 | LOXL2 (0.50) | CYP4A11LOXL2CYP4F2MEN1KMT2A | |
| SCHEMBL4247366 | 0.77 | GBA1 (0.51) | CYP4A11LOXL2CYP4F2EPHX1MEN1 | |
| SCHEMBL27979790 | 0.76 | KMT2A (0.50) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4777910 | 0.76 | GBA1 (0.50) | CYP4A11LOXL2CYP4F2EPHX1MEN1 | |
| SCHEMBL3699320 | 0.75 | GBA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |