Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812600 | 0.87 | KMT2A (0.56) | KMT2AMEN1GRIK1ALDH1A1GAA | |
| SCHEMBL27540930 | 0.83 | PTGER4 (0.46) | KMT2AALDH1A1 | |
| SCHEMBL11228193 | 0.82 | KMT2A (0.58) | KMT2AMEN1GRIK1ALDH1A1GAA | |
| Bicarbonate SCHEMBL2854194 | 0.82 | GBA1 (0.52) | KMT2AMEN1GAA | |
| SCHEMBL6794966 | 0.81 | LOXL2 (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL4364820 | 0.80 | ESR2 (0.53) | — | |
| SCHEMBL5675291 | 0.80 | GBA1 (0.57) | ALDH1A1 | |
| SCHEMBL28852917 | 0.79 | GAA (0.57) | KMT2AMEN1GAA | |
| SCHEMBL11590207 | 0.79 | GRIK1 (0.53) | KMT2AMEN1GRIK1ALDH1A1GAA | |
| SCHEMBL13687812 | 0.79 | KMT2A (0.50) | KMT2AMEN1GRIK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459227-B | 4-azetidinyl-1-phenyl-cyclohexane antagonists of ccr2 | JANSSEN PHARMACEUTICA NV | 2014-08-20 | — | — | CN | disclosed |