Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092643 | 0.83 | MEN1 (0.33) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL22042405 | 0.83 | MEN1 (0.33) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL30790709 | 0.72 | HRH3 (0.50) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31383394 | 0.68 | CYP2C19 (0.58) | CHRM4 | |
| SCHEMBL9499780 | 0.67 | ALDH1A1 (0.52) | MAPTPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL30790748 | 0.67 | HRH3 (0.53) | TP53MEN1KMT2AKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL9503509 | 0.66 | ALDH1A1 (0.51) | MAPTPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL2766678 | 0.65 | FFAR4 (0.54) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30790747 | 0.65 | HRH3 (0.53) | MAPTMEN1KMT2AKDM4ECHRM4 | |
| SCHEMBL30790763 | 0.65 | HRH4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |