Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1292809 | 0.90 | NAMPT (0.44) | NAMPTL3MBTL1ALDH1A1EPHX2TLR9 | |
| SCHEMBL19541464 | 0.84 | L3MBTL1 (0.46) | NAMPTL3MBTL1ALDH1A1POLB | |
| SCHEMBL15934102 | 0.81 | GAA (0.46) | NAMPTL3MBTL1CYP1A2POLBMAPT | |
| SCHEMBL14654219 | 0.79 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1POLBFKBP1A | |
| SCHEMBL12706442 | 0.79 | L3MBTL1 (0.42) | NAMPTL3MBTL1ALDH1A1EPHX2TLR9 | |
| SCHEMBL16826963 | 0.78 | TPSAB1 (0.44) | NAMPTL3MBTL1ALDH1A1EPHX2TLR9 | |
| SCHEMBL15932285 | 0.77 | NAMPT (0.40) | NAMPTL3MBTL1ALDH1A1EPHX2TLR9 | |
| SCHEMBL16826909 | 0.76 | NAMPT (0.46) | NAMPTL3MBTL1ALDH1A1EPHX2TLR9 | |
| SCHEMBL16826752 | 0.74 | USP2 (0.45) | NAMPTALDH1A1EPHX2POLBMEN1 | |
| SCHEMBL18590382 | 0.74 | USP2 (0.45) | NAMPTALDH1A1EPHX2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689875-B1 | USE OF TRIAZOLOPYRIMIDINE, TRIAZOLOPYRIDINE COMPOUNDS AND COMPOSITION THEREOF FOR TREATING PRC2-MEDIATED DISEASES | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2021-10-13 | — | — | EP | disclosed |