Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164872 | 0.83 | TP53 (0.48) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL17733556 | 0.79 | TP53 (0.44) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL10089286 | 0.77 | TP53 (0.52) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL29381439 | 0.77 | TP53 (0.52) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL7646369 | 0.74 | TP53 (0.39) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL11226028 | 0.73 | TP53 (0.38) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL24377620 | 0.70 | TP53 (0.35) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL29382915 | 0.70 | TP53 (0.44) | TP53TSHRCYP3A4HSD17B10MAPK1 | |
| SCHEMBL8172417 | 0.69 | P2RX7 (0.34) | TP53TSHRCYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL30133368 | 0.67 | TP53 (0.41) | TP53TSHRCYP3A4HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |