Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646369 | 0.76 | TP53 (0.39) | TP53TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL16499836 | 0.74 | HPGD (0.39) | TSHRHSD17B10 | |
| SCHEMBL29568949 | 0.74 | GAA (0.37) | — | |
| SCHEMBL24377799 | 0.74 | GAA (0.37) | — | |
| SCHEMBL3164872 | 0.72 | TP53 (0.48) | TP53TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL29568710 | 0.71 | — | — | |
| SCHEMBL15072429 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL20220050 | 0.71 | MAPT (0.35) | — | |
| SCHEMBL16321657 | 0.70 | — | — | |
| SCHEMBL23912800 | 0.70 | TP53 (0.46) | TP53TSHRMAPK1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084990-A1 | METHODS FOR THE PREPARATION OF PYRAZOLO[3,4-D]PYRIMIDIN-4-ONES AND INTERMEDIATES USED THEREIN | ADAMA MAKHTESHIM LTD. (IL) | 2022-04-28 | — | — | WO | disclosed |