Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | FES | P07332 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924242 | 0.78 | MAPT (0.37) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL5511635 | 0.76 | ALK (0.45) | ALPLPIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL22246876 | 0.75 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL21513586 | 0.73 | OPRK1 (0.33) | — | |
| SCHEMBL20924105 | 0.73 | NPC1 (0.38) | ALPLPIK3CDPIK3CAMTORALDH1A1 | |
| SCHEMBL9953579 | 0.72 | ALDH1A1 (0.38) | ALPLPLK4AURKAJAK2ROCK2 | |
| SCHEMBL22246975 | 0.72 | PIK3CG (0.42) | ALPLPIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL22246887 | 0.71 | NPC1 (0.46) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL731743 | 0.70 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL22246978 | 0.69 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |