Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 18/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156096 | 0.81 | ITGAV (0.67) | ITGAVITGB6ITGB3ITGB1ITGA4 | |
| SCHEMBL20156298 | 0.80 | ITGAV (0.57) | ITGAVITGB6ITGB3CXCR4 | |
| SCHEMBL20156248 | 0.76 | ITGAV (0.44) | ITGAVITGB6ITGB3CXCR4 | |
| SCHEMBL20156054 | 0.76 | ITGAV (0.47) | ITGAVITGB6ITGB3CXCR4ITGB1 | |
| SCHEMBL20156009 | 0.75 | CXCR4 (0.47) | ITGAVITGB6ITGB3CXCR4 | |
| SCHEMBL20156297 | 0.75 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA4 | |
| SCHEMBL20156008 | 0.73 | ITGAV (0.53) | ITGAVITGB6ITGB3CXCR4 | |
| SCHEMBL20156094 | 0.72 | ITGAV (0.49) | ITGAVITGB6ITGB3CXCR4 | |
| SCHEMBL24363128 | 0.69 | ITGAV (0.61) | ITGAVITGB6ITGB3ITGB1ITGA4 | |
| SCHEMBL21272499 | 0.69 | ITGAV (0.53) | ITGAVITGB6ITGB3ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |