Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 14/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156242 | 0.83 | CXCR4 (0.52) | ITGAVITGB3ITGB6CXCR4 | |
| SCHEMBL20156282 | 0.83 | ITGB3 (0.57) | ITGAVITGB3ITGB6 | |
| SCHEMBL20156034 | 0.81 | ITGAV (0.49) | ITGAVITGB3ITGB6 | |
| SCHEMBL20156301 | 0.80 | ITGB3 (0.57) | ITGAVITGB3ITGB6ITGA2B | |
| SCHEMBL20156251 | 0.78 | ITGAV (0.50) | ITGAVITGB3ITGB6 | |
| SCHEMBL20156245 | 0.77 | ITGAV (0.54) | ITGAVITGB3ITGB6CXCR4ITGA2B | |
| SCHEMBL20156349 | 0.77 | ITGB3 (0.49) | ITGAVITGB3ITGB6CXCR4ITGA2B | |
| SCHEMBL20156250 | 0.77 | ITGAV (0.52) | ITGAVITGB3ITGB6 | |
| SCHEMBL20156247 | 0.77 | ITGAV (0.52) | ITGAVITGB3ITGB6CXCR4ITGA2B | |
| SCHEMBL20156053 | 0.75 | ITGB3 (0.54) | ITGAVITGB3ITGB6CXCR4ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |