Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913761 | 0.89 | TSHR (0.52) | TSHRMAPTSMN1; SMN2GAAPPARG | |
| SCHEMBL28862575 | 0.81 | TSHR (0.47) | TSHRMAPTSMN1; SMN2GAAPPARG | |
| SCHEMBL9239313 | 0.81 | MGAM (0.50) | TSHRMAPTSMN1; SMN2GAAMGAM | |
| SCHEMBL5859548 | 0.81 | MGAM (0.50) | TSHRMAPTSMN1; SMN2GAAMGAM | |
| SCHEMBL16044330 | 0.79 | TSHR (0.58) | TSHRMAPTSMN1; SMN2GAAPPARG | |
| SCHEMBL28235998 | 0.77 | TSHR (0.50) | TSHRMAPTSMN1; SMN2GAAPPARG | |
| SCHEMBL28733880 | 0.77 | MAPT (0.50) | TSHRMAPTSMN1; SMN2GAAMGAM | |
| SCHEMBL5860234 | 0.76 | MGAM (0.44) | TSHRMAPTSMN1; SMN2GAAMGAM | |
| SCHEMBL9239320 | 0.76 | MAPT (0.47) | TSHRMAPTSMN1; SMN2GAAMGAM | |
| SCHEMBL9239317 | 0.76 | MAPT (0.47) | TSHRMAPTSMN1; SMN2GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332432-B2 | Bioenergetically active esters for health and disease | UNIVERSITY OF KANSAS (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210317067-A1 | BIOENERGETICALLY ACTIVE ESTERS FOR HEALTH AND DISEASE | UNIVERSITY OF KANSAS | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332432-B2 | Bioenergetically active esters for health and disease | PC, ME2, CPT2 | TSHR 4404/4885MAPT 289/4885SMN1; SMN2 171/4885 |
| US-20210317067-A1 | BIOENERGETICALLY ACTIVE ESTERS FOR HEALTH AND DISEASE | PC, ME2, CPT2 | TSHR 4404/4885MAPT 289/4885SMN1; SMN2 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.